Clinical implications of angiogenesis in cancers
نویسندگان
چکیده
منابع مشابه
Clinical Implications of Angiogenesis in Cancers
Angiogenesis plays an important role in the growth and progression of cancer. The regulation of tumor angiogenesis depends on a net balance of angiogenic factors and antiangiogenic factors, which are secreted by both tumor cells and host-infiltrating cells. Numerous studies have indicated that assessment of angiogenic activity by either microvessel density or expression of angiogenic factors in...
متن کاملClinical implications of expression of ETS-1 related to angiogenesis in uterine endometrial cancers.
BACKGROUND Angiogenesis is essential for development, growth and advancement of solid tumors. During angiogenesis, ETS-1 is strongly expressed in vascular endothelial cells and the adjacent interstitial cells, while the inhibition of ETS-1 expression leads to suppression of angiogenesis. This prompted us to study the clinical implications of ETS-1 in relation to angiogenesis in uterine endometr...
متن کاملAngiogenesis in Uterine Cervical Cancers Clinical Implications of Expression of Interleukin 8 Related to
There was a significant correlation between microvessel counts and interleukin (IL)-8 levels and between infiltrated macrophage counts and IL-8 levels in uterine cervical cancers. Immunohistochemical staining revealed that the localization of IL-8 was similar to that of CD68 for macrophages. The prognosis of the 20 patients with high IL-8 (>1000 pg/mg protein) in uterine cervical cancers was ex...
متن کاملClinical implications of expression of interleukin 8 related to angiogenesis in uterine cervical cancers.
There was a significant correlation between microvessel counts and interleukin (IL)-8 levels and between infiltrated macrophage counts and IL-8 levels in uterine cervical cancers. Immunohistochemical staining revealed that the localization of IL-8 was similar to that of CD68 for macrophages. The prognosis of the 20 patients with high IL-8 (>1000 pg/mg protein) in uterine cervical cancers was ex...
متن کاملTumor Angiogenesis in Breast Cancer: Clinical Implications
Angiogenesis, the formation of new blood vessels from pre-existing ones represents a critical aspect of tumor progression and metastasis. Because inhibition of angiogenesis represents a major approach to cancer treatment, the development of inhibitors of angiogenesis is a major challenge. Therefore, inhibition of angiogenesis is an attractive strategy for treatment of cancer. Currently, the mos...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Vascular Health and Risk Management
سال: 2006
ISSN: 1176-6344
DOI: 10.2147/vhrm.2006.2.2.97